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CEA antibody
分类 肿瘤标志物
Parameters
产品别名：Carcinoembryonic antigen (CEA), also known as CEACAM-5 and CD66e
免疫原：Human CEA
货号：SLS-102-02
克隆类型：E2-18
亚型：IgG1
规格：1mg/支
浓度：2-3mg/ml
配对：This antibody can be used for solid phase coating when paired with SLS-102-04.or This antibody can be used for conjugation when paired with monoclonal antibody SLS-102-01
纯度：>95% pure(SDS-PAGE).
批号：随货见
状态和缓冲液：0.01M PBS, 0.9% NaCl, pH 7.4
存储&安全
存储：Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles.
CEA is restricted to the apical face of intestinal epithelial cells in the adult but is more diffuse during embryonic development and in tumors. This is consistent with a role in the development and maintenance of epithelial architecture. CEA is upregulated in a wide variety of human tumors and is a commonly used cancer marker. It promotes tumor cell migration, invasion, adhesion, and metastasis. It also contributes to tumor formation by maintaining cellular proliferation in the presence of differentiation stimuli, and by blocking apoptosis following loss of ECM anchorage (anoikis).
Description
CEA is restricted to the apical face of intestinal epithelial cells in the adult but is more diffuse during embryonic development and in tumors. This is consistent with a role in the development and maintenance of epithelial architecture. CEA is upregulated in a wide variety of human tumors and is a commonly used cancer marker. It promotes tumor cell migration, invasion, adhesion, and metastasis. It also contributes to tumor formation by maintaining cellular proliferation in the presence of differentiation stimuli, and by blocking apoptosis following loss of ECM anchorage (anoikis).相关商品