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3

SCC antibody

Parameters

产品别名:Serpin B3, also known as Squamous Cell Carcinoma Antigen-1 (SCCA1)

免疫原:Human SCC

试验图片:/Uploads/Image/201709/f6fcc3fb9a94fa205e87153daa976ce5b3c76da5.png

货号:SLS-113-04

克隆类型:S4-31

亚型:IgG1

规格:1mg/支

浓度:2-3mg/ml

配对:This antibody can be used for conjugation when paired with monoclonal antibody SLS-113-01、SLS-113-02、SLS-113-03.

纯度:>95% pure(SDS-PAGE).

批号:随货见

状态和缓冲液:0.01M PBS, 0.9% NaCl, pH 7.4

存储&安全

存储:Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles.

Serpins primarily inhibit serine proteases and some are known to inhibit caspases and papain-like cysteine proteases. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. Serpin B3 was initially isolated from human cervical squamous cell tissue. It is a tumor marker for squamous cell carcinomas in various areas including the cervix, head, neck and lung. Unlike typical serpins, Serpin B3 shows inhibitory activity against papain-like lysosomal cysteine proteases Cathepsin K, L, and S, while lacking inhibitory activity against serine proteases.

Description

Serpins primarily inhibit serine proteases and some are known to inhibit caspases and papain-like cysteine proteases. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. Serpin B3 was initially isolated from human cervical squamous cell tissue. It is a tumor marker for squamous cell carcinomas in various areas including the cervix, head, neck and lung. Unlike typical serpins, Serpin B3 shows inhibitory activity against papain-like lysosomal cysteine proteases Cathepsin K, L, and S, while lacking inhibitory activity against serine proteases.

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