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Rabbit-anti NPC2 monoclonal antibody
分类 新陈代谢
参数
货号:SLS-NPC2-01B
别名:NPC2,HE1
克隆号:UN8SY
物种:Human
来源:Rabbit
免疫原:Recombinant human NPC2
识别位点:NPC2
亚型:Rabbit IgG
配对:Biotin
规格:25ug, 50ug, 100ug, >100ug/vial
浓度:>1mg/ml
状态和缓冲液:liquid,0.22μm filtered solution in 20mM hepes7.4, 150mm NaCl, 50% glycerin,0.03% proclin.
纯度:Greater than 95%, as determined by SDS-PAGE.
交叉反应:1.HepG2 cells were intracellularly-stained with SLS-NPC2-01B (red) or an isotype control (green), followed by SLS-7QK-01 goat anti-rabbit secondary antibodies. Non-fluorescently stained cells were used as blank control(black line).
2.Flow cytometry analysis of NPC2 overexpressed 293F cells with SLS-NPC2-01B , followed by goat anti-rabbit-SLS-7QK-01 (red). The isotype control is green. The vertical axis indicates the antigen protein expression level.
保存条件:Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles
用途:ELISA,FACS,IF,IHC; Research Areas: Metabolism
使用建议:This product is only for the in vitro study, not intended for diagnostic use, please according to the laboratory standard operating procedures using.
实验照片
描述
Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment . Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1 .相关商品
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