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Rabbit-anti BMP10 monoclonal antibody

参数

货号:SLS-BMP10-02B

别名:BMP10

克隆号:U6FP

物种:Human

来源:Rabbit

免疫原:Recombinant human BMP10

识别位点:BMP10

亚型:Rabbit IgG

配对:Biotin

规格:25ug, 50ug, 100ug, >100ug/vial

浓度:>1mg/ml

状态和缓冲液:liquid,0.22μm filtered solution in 20mM hepes7.4, 150mm NaCl, 50% glycerin,0.03% proclin.

纯度:Greater than 95%, as determined by SDS-PAGE.

交叉反应:1.Flow cytometry analysis of BMP10 overexpressed 293F cells with SLS-BMP10-02B , followed by goat anti-rabbit-SLS-M4D8-02 (red). The isotype control is green. The vertical axis indicates the antigen protein expression level.
2.Flow cytometry analysis of BMP10 overexpressed 293F cells with SLS-BMP10-02B, followed by goat anti-rabbit IgG-SLS-M4D8-02 (red line) . The isotype control is green.

保存条件:Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles

用途:ELISA,IF; Research Areas: Developmental Biology, Cardiovascular Research

使用建议:This product is only for the in vitro study, not intended for diagnostic use, please according to the laboratory standard operating procedures using.

实验照片

Rabbit-anti BMP10 monoclonal antibody Rabbit-anti BMP10 monoclonal antibody
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors.

描述

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors.

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