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Rabbit-anti CCR2 monoclonal antibody

分类 信号转导

参数

货号:SLS-CCR2-01N

别名:CCR2,CMKBR2

克隆号:FPAB

物种:Human

来源:Rabbit

免疫原:Recombinant human CCR2

识别位点:CCR2

亚型:Rabbit IgG

配对:No Conjugates

规格:25ug, 50ug, 100ug, >100ug/vial

浓度:>1mg/ml

状态和缓冲液:liquid,0.22μm filtered solution in 20mM hepes7.4, 150mm NaCl, 50% glycerin,0.03% proclin.

纯度:Greater than 95%, as determined by SDS-PAGE.

交叉反应:1.PBMC cells were stained with SLS-CCR2-01N (right) or an isotype control (left), followed by SLS-7QK-01 conjugated goat anti-rabbit secondary antibodies.

保存条件:Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles

用途:FACS; Research Areas: Signal Transduction

使用建议:This product is only for the in vitro study, not intended for diagnostic use, please according to the laboratory standard operating procedures using.

Key functional receptor for CCL2 but can also bind CCL7 and CCL12 . Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable).

描述

Key functional receptor for CCL2 but can also bind CCL7 and CCL12 . Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable).

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