Streptococcus pyogenes Streptolysin O (slo)

下载产品说明书 产品概要

免疫原	recombinant

产品参数

货号	44700
克隆类型	recombinant
规格	0.1 mg
纯度	>95% pure(SDS-PAGE).
批号	随货见
状态和缓冲液	0.01M PBS, 0.9% NaCl, pH 7.4

使用建议 & 方法学

应用	This product is only for the in vitro study, not intended for diagnostic use, please according to the laboratory standard operating procedures using.
使用建议	Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

存储 & 安全

存储	Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles.

产品描述

Extracellular protein streptolysin O is a key virulence factor of group A streptococci and belongs to the beta-barrel pore-forming exotoxin family called thiol-activated cholesterol-dependent cytolysins (CDCs). After secretion, it binds to the host erythrocyte membranes forming ring-like structures. The presence of cholesterol in the target membrane is required for pore formation which finally results in cytolysis.