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产品描述 | Serpins primarily inhibit serine proteases and some are known to inhibit caspases and papain-like cysteine proteases. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. Serpin B3 was initially isolated from human cervical squamous cell tissue. It is a tumor marker for squamous cell carcinomas in various areas including the cervix, head, neck and lung. Unlike typical serpins, Serpin B3 shows inhibitory activity against papain-like lysosomal cysteine proteases Cathepsin K, L, and S, while lacking inhibitory activity against serine proteases. |
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产品别名 | Serpin B3, also known as Squamous Cell Carcinoma Antigen-1 (SCCA1) |
免疫原 | Human SCC |
货号 | SLS-113-03 |
克隆类型 | S4-7 |
亚型 | IgG1 |
规格 | 1mg/支 |
浓度 | 2-3mg/ml |
配对 | This antibody can be used for solid phase coating when paired with SLS-113-04. |
纯度 | >95% pure(SDS-PAGE). |
批号 | 随货见 |
状态和缓冲液 | 0.01M PBS, 0.9% NaCl, pH 7.4 |
使用建议 | Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. |
应用 | This product is only for the in vitro study, not intended for diagnostic use, please according to the laboratory standard operating procedures using. |
存储 | Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles. |